This research aims to investigate the impact of comprehensive risk management and digital transformation on sustainable banking with the moderating role of knowledge management. A questionnaire including 38 questions with a five-point Likert scale was used to collect data. First, the questionnaire was confirmed from the point of view of experts in terms of content validity. Then construct validity was also done using the confirmatory factor analysis technique. The AVE value of all variables was above 0.5 and convergent validity was confirmed. Cronbach's alpha coefficient and composite reliability were also calculated to measure reliability. Cronbach's alpha coefficient and CR value of all variables are above 0.7. Therefore, the reliability of the questionnaire has been evaluated favorably. The statistical population of this research is the managers and experts of the banking industry, which due to the unlimited population, the final sample was 350 people using Cochran's formula. Partial least squares technique and Smart Pls software have been used to test the research hypotheses. The obtained results showed that comprehensive risk management and digital transformation have an impact on sustainable banking. Also, knowledge management has an effect on the relationship between comprehensive risk management and sustainable banking. And knowledge management has an effect on the relationship between digital transformation and sustainable banking.